{"id":6479,"date":"2020-05-04T09:25:01","date_gmt":"2020-05-04T08:25:01","guid":{"rendered":"https:\/\/euromedic.rs\/pregledi\/neurologija-epilepsija-i-trudnoca-copy\/"},"modified":"2020-10-07T10:53:55","modified_gmt":"2020-10-07T09:53:55","slug":"gastroenterologija-autoimune-bolesti-jetre","status":"publish","type":"post","link":"https:\/\/euromedic.rs\/pregledi\/specijalisticki-pregledi\/gastroenterologija\/gastroenterologija-autoimune-bolesti-jetre\/","title":{"rendered":"Gastroenterologija – Autoimune bolesti jetre"},"content":{"rendered":"

Autoimune bolesti jetre su zapaljenjske bolesti izazvane imunskim odgovorom\u00a0organizma koji se prema jetri pona\u0161a kao prema stranom telu. Uzroci ovog\u00a0oboljenja su nepoznati ali se smatra da ulogu imaju nasledni faktori, virusi, neki od
\nlekova. Karakteristika ovih bolesti je \u0161to se one te\u0161ko prepoznaju, progresivne su i\u00a0imaju svoj tok. Kod le\u010denih to je – remisija, kada simptomi uglavnom is\u010dezavaju i\u00a0relaps kada se simptomi vra\u0107aju. Kod nele\u010denih tok bolesti vodi ka cirozi jetre\u00a0(stvaranje o\u017eiljaka u jetri) koja na kraju se zavr\u0161ava akutnim propadanjem jetre\u00a0tzv. insuficijencijom, a u 50% slu\u010dajeva vodi ka smrtnom ishodu. Obolevaju\u00a0uglavnom \u017eene srednje \u017eivotne dobi,op\u0161ta rasprostranjenost bolesti 16 \/100 000.<\/p>\n

Dele se na:<\/strong>
\n1. Autoimuni hepatitis
\n2. PBC (primarni bilijarni holangitis)
\n3. PSC (primarni skleroziraju\u0107i holingitis)
\n4. Preklapaju\u0107e bolesti jetre (gde se simptomi ovih obolenja preklapaju)
\n5. Autoimuna reakcija jetre u sklopu drugih bolesti (glutenska enteropatija,\u00a0Haschimoto tireoiditis, C hepatitis i dr.)<\/p>\n

Simptomi bolesti su uglavnom sli\u010dni: umor, malaksalost, mu\u010dnina, povra\u0107anje,\u00a0\u017eutica, bol pod desnim rebarnim lukom, tamno prebojena mokra\u0107a i dr.\u00a0Pregledom stomaka nalazimo na uve\u0107anu bolnu jetru i slezinu, otok stomaka kao
\ni otok nogu i dr.<\/p>\n

Dijagnoza se postavlja na osnovu:<\/strong>
\n1.Laboratorijeske analize (povi\u0161eni jetrini enzimi i bilirubin); povi\u0161ena antitela u\u00a0krvi (antitela protiv glatkih mi\u0161i\u0107a, protiv jetre – ANA, ASMA, LK1 i dr.
\n2 . Eho gornjeg abdomena
\n3. Magnetna rezonanca jetre i \u017eu\u010dnih puteva<\/p>\n

4.ERCP – dijagnostika opstrukcije ve\u0107ih \u017eu\u010dnih puteva i postavljanje stentova \u0161to je
\nujedno i terapijski postupak.
\n5. Biopsija jetre i uzimanje uzoraka (zlatni standard)<\/p>\n

Le\u010denje:<\/strong>
\n1.Imunosupresivni lekovi (spre\u010davaju odgovor organizma koji je odgovoran za\u00a0upalu jetre)
\na.kortikosteroidi – hormonski lekovi koji su efikasni ali imaju niz nus pojava kao \u0161to\u00a0su hipertenzija, gojaznost, osteoporoza
\nb.Imuran – lek koji ima nus pojavu smanjivanje broja leukocita i trombocita.
\n2.Ursofalk- lek koji poma\u017ee smanjenju \u017eutIce
\n3.Transplantacija jetre (u slu\u010daju da medikamentozno le\u010denje nema efekta)<\/p>\n

Naravno pod ovim se podrazumeva i upraznjvanje strogog dijetetsko higijenskog\u00a0re\u017eima ishrane (koji \u0107e prepisati na\u0161i dijeteti\u010dari) uz, zabranu alkohola i lekova\u00a0koji o\u0161te\u0107uju jetru.
\nS obzirom da nele\u010dena bolest vodi u krajnjem toku ka smrtnom ishodu a simptomi\u00a0mogu trajati i do 10 godina dok se ne postavi dijagnoza, prednost na\u0161e ustanove –\u00a0Euromedika je u postojanju adekvatnog tima stru\u010dnjaka i odgovaraju\u0107e\u00a0dijagnostike koji ovu bolest mo\u017ee na vreme prepoznati I le\u010diti, a samim tim\u00a0spre\u010diti krajnje ne\u017eeljeni ishod ove bolesti.<\/p>\n

Zaka\u017eite Va\u0161 specijalisti\u010dki pregled gastroenterologa.\u00a0<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Autoimune bolesti jetre su zapaljenjske bolesti izazvane imunskim odgovorom\u00a0organizma koji se prema jetri pona\u0161a kao…<\/p>\n","protected":false},"author":1,"featured_media":6481,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[479],"tags":[415,76],"class_list":["post-6479","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-gastroenterologija","tag-bolesti-jetre","tag-gastroenterologija"],"yoast_head":"\nGastroenterologija - Autoimune bolesti jetre - DIjagnostika i le\u010denje<\/title>\n<meta name=\"description\" content=\"Autoimune bolesti jetre su zapaljenjske bolesti izazvane imunskim odgovorom\u00a0organizma koji se prema jetri pona\u0161a kao prema stranom telu. 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